3-tert-Butylbenzene boronic acid

3-tert-Butylbenzene boronic acid - Names and Identifiers

Name	(3-tert-butylphenyl)boronic acid
Synonyms	M-T-BUTYLPHENYLBORONIC ACID 3-tert-Butylphenylboronicaci 3-tert-Butylphenylboronic acid 3-tert-Butylbenzene boronic acid (3-tert-butylphenyl)boronic acid (3-tert-Butylphenyl)boronic acid Boronic acid, B-[3-(1,1-dimethylethyl)phenyl]- 3-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride)
CAS	560132-24-3
InChI	InChI=1/C10H15BO2/c1-10(2,3)8-5-4-6-9(7-8)11(12)13/h4-7,12-13H,1-3H3

3-tert-Butylbenzene boronic acid - Physico-chemical Properties

Molecular Formula	C10H15BO2
Molar Mass	178.04
Density	1.02±0.1 g/cm3(Predicted)
Melting Point	221 °C(Solv: water (7732-18-5))
Boling Point	304.3±35.0 °C(Predicted)
Flash Point	137.866°C
Vapor Presure	0mmHg at 25°C
pKa	8?+-.0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.511

3-tert-Butylbenzene boronic acid - Risk and Safety

Risk Codes	41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

3-tert-Butylbenzene boronic acid - Introduction

(3-tert-butylphenyl)boronic acid is an organic compound with the chemical formula C10H15BO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: white crystal or crystalline powder
2. Melting point: about 110-112°C
3. Solubility: Soluble in chloroform, methanol and dichloromethane, low solubility in water.

Use:
1. Tert-butylphenylboronic acid is one of the important boron reagents in organic synthesis, which can be used as a borylation reagent for phenols and aromatic hydrocarbons.
2. It can be used for the preparation of catalysts, the borylation of halogenated aromatic hydrocarbons, the formation of C- C bonds, and the synthesis of natural products.

Preparation Method:
1. tert-butylphenylboronic acid can be obtained by reacting phenylboronic acid with 3-tert-butylphenyllithium in an aminoethanol solution.
2. Another preparation method is to react terephthalic acid with tert-butyl lithium in tetraethylether to produce p-tert-butylphenyl lithium, and then react with trichloroborane to obtain (3-tert-butylphenyl)boronic acid.

Safety Information:
1. (3-tert-butylphenyl)boronic acid generally does not cause obvious harm under normal use conditions.
2. It should be away from fire and oxidant.
3. Wear appropriate protective measures when using, such as safety glasses and gloves.
4. such as inhalation or contact with the skin, should immediately rinse with plenty of water. If you feel unwell, you should seek medical help.

Last Update：2024-04-10 22:29:15